Restle, Tobias: search on Z-Library

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1

A Single Inter-Domain Salt Bridge within the Human Argonaute 2 Protein Crucially Affects Protein Folding and Consequently Enzymatic Activity

Kalia, Munishikha, Willkomm, Sarah, Christian Claussen, Jens, Bonvin, Alexandre M.J.J., Restle, Tobias

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

2

Biochemical and Pre-Steady-State Kinetic Characterization of the Hepatitis C Virus RNA Polymerase (NS5BΔ21, HC-J4) †

Cramer, Janina, Jaeger, Joachim, Restle, Tobias

Journal:

Year:

2006

Language:

english

File:

PDF, 213 KB

english, 2006

3

Implications of Active Site Constraints on Varied DNA Polymerase Selectivity

Strerath, Michael, Cramer, Janina, Restle, Tobias, Marx, Andreas

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 45 KB

english, 2002

4

Small Molecule Inhibitors Targeting HIV-1 Reverse Transcriptase Dimerization

Dina Grohmann, Valentina Corradi, Mira Elbasyouny, Annika Baude, Florian Horenkamp, Sandra D. Laufer, Fabrizio Manetti, Maurizio Botta, Tobias Restle

Journal:

Year:

2008

Language:

english

File:

PDF, 665 KB

english, 2008

5

Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein

Willkomm, Sarah, Oellig, Christine A., Zander, Adrian, Restle, Tobias, Keegan, Ronan, Grohmann, Dina, Schneider, Sabine

Journal:

Nature Microbiology

Year:

2017

Language:

english

File:

PDF, 7.61 MB

english, 2017

6

Novel Insights into Guide RNA 5′-Nucleoside/Tide Binding by Human Argonaute 2

Kalia, Munishikha, Willkomm, Sarah, Claussen, Jens, Restle, Tobias, Bonvin, Alexandre

Journal:

International Journal of Molecular Sciences

Year:

2015

Language:

english

File:

PDF, 3.33 MB

english, 2015

7

A toolkit and benchmark study for FRET-restrained high-precision structural modeling

Kalinin, Stanislav, Peulen, Thomas, Sindbert, Simon, Rothwell, Paul J, Berger, Sylvia, Restle, Tobias, Goody, Roger S, Gohlke, Holger, Seidel, Claus A M

Journal:

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

8

Recent Developments in Peptide-Based Nucleic Acid Delivery

Veldhoen, Sandra, Laufer, Sandra D., Restle, Tobias

Journal:

International Journal of Molecular Sciences

Year:

2008

Language:

english

File:

PDF, 1.30 MB

english, 2008

9

Opposed Steric Constraints in Human DNA Polymerase β and E. coli DNA Polymerase I

Pasquale, Francesca Di, Fischer, Daniela, Grohmann, Dina, Restle, Tobias, Geyer, Armin, Marx, Andreas

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

10

Pre-Steady-State Kinetic Characterization of RNA-Primed Initiation of Transcription by HIV-1 Reverse Transcriptase and Analysis of the Transition to a Processive DNA-Primed Polymerization Mode †

Krebs, Ruth, Wöhrl, Birgitta M., Cellai, Luciano, Goody, Roger S., Restle, Tobias

Journal:

Year:

1998

Language:

english

File:

PDF, 131 KB

english, 1998

11

Varied Active-Site Constraints in the Klenow Fragment of E. coli DNA Polymerase I and the Lesion-Bypass Dbh DNA Polymerase

Janina Cramer, Gopinath Rangam, Andreas Marx, Tobias Restle

Journal:

Year:

2008

File:

PDF, 56 KB

2008

12

FRET-based assay to screen inhibitors of HIV-1 reverse transcriptase and nucleocapsid protein

Sharma, Kamal K., Przybilla, Frédéric, Restle, Tobias, Godet, Julien, Mély, Yves

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

13

Analysis of the Polymerization Kinetics of Homodimeric EIAV p51/51 Reverse Transcriptase Implies the Formation of a Polymerase Active Site Identical to Heterodimeric EIAV p66/51 Reverse Transcriptase †

Souquet, Manfred, Restle, Tobias, Krebs, Ruth, Le Grice, Stuart F. J., Goody, Roger S., Wöhrl, Birgitta M.

Journal:

Year:

1998

Language:

english

File:

PDF, 105 KB

english, 1998

14

Varied Active-Site Constraints in the Klenow Fragment of E. coli DNA Polymerase I and the Lesion-Bypass Dbh DNA Polymerase

Janina Cramer, Gopinath Rangam, Andreas Marx, Tobias Restle

Journal:

Year:

2008

Language:

english

File:

PDF, 311 KB

english, 2008

15

Wie Gene abgelesen werden

Tobias Restle, Georg Sczakiel

Journal:

Chemie in unserer Zeit

Year:

2006

Language:

german

File:

PDF, 277 KB

german, 2006

16

Refined model for primer/template binding by HIV-1 reverse transcriptase: pre-steady-state kinetic analyses of primer/template binding and nucleotide incorporation events distinguish between different binding modes depending on the nature of the nucleic acid substrate

Birgitta M Wöhrl, Ruth Krebs, Roger S Goody, Tobias Restle

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 266 KB

english, 1999

17

Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity

Xiao, Yibei, Ma, Qingjun, Restle, Tobias, Shang, Weifeng, Svergun, Dmitri I., Ponnusamy, Rajesh, Sczakiel, Georg, Hilgenfeld, Rolf

Journal:

Journal of Virology

Year:

2012

Language:

english

File:

PDF, 2.68 MB

english, 2012

18

Insight into the Mechanism of a Peptide Inhibitor of HIV Reverse Transcriptase Dimerization †

Depollier, Julien, Hourdou, Marie-Laure, Aldrian-Herrada, Gudrun, Rothwell, Paul, Restle, Tobias, Divita, Gilles

Journal:

Year:

2005

Language:

english

File:

PDF, 551 KB

english, 2005

19

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: From nucleocapsid-condensed RNA to Vpr-bridged DNA

Lyonnais, Sébastien, Gorelick, Robert J., Heniche-Boukhalfa, Fatima, Bouaziz, Serge, Parissi, Vincent, Mouscadet, Jean-François, Restle, Tobias, Gatell, Jose Maria, Le Cam, Eric, Mirambeau, Gilles

Journal:

Year:

2013

Language:

english

File:

PDF, 2.92 MB

english, 2013

20

Interaction of fluorescently labeled dideoxynucleotides with HIV-1 reverse transcriptase

Mueller, Barbara, Restle, Tobias, Reinstein, Joachim, Goody, Roger S.

Journal:

Year:

1991

Language:

english

File:

PDF, 877 KB

english, 1991

21

Studies on the Interaction between HIV-1 Reverse Transcriptase and Templateoligo α-Thymidylate Duplexes

Maury, Georges, Rayner, Bernard, Imbach, Jean-Louis, Müller, Barbara, Restle, Tobias, Goody, Roger S.

Journal:

Nucleosides and Nucleotides

Year:

1991

Language:

english

File:

PDF, 206 KB

english, 1991

22

HIV-1 Nucleocapsid Traps Reverse Transcriptase on Nucleic Acid Substrates †

Grohmann, Dina, Godet, Julien, Mély, Yves, Darlix, Jean-Luc, Restle, Tobias

Journal:

Year:

2008

Language:

english

File:

PDF, 1.45 MB

english, 2008

23

Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties

Willkomm, Sarah, Zander, Adrian, Grohmann, Dina, Restle, Tobias, Yuan, Y. Adam

Journal:

Year:

2016

Language:

english

File:

PDF, 4.26 MB

english, 2016

24

Aptamer Displacement Identifies Alternative Small-Molecule Target Sites that Escape Viral Resistance

Satoko Yamazaki, Lu Tan, Günter Mayer, Jörg S. Hartig, Jin-Na Song, Sandra Reuter, Tobias Restle, Sandra D. Laufer, Dina Grohmann, Hans-Georg Kräusslich, Jürgen Bajorath, Michael Famulok

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 1006 KB

english, 2007

25

Conformational Dynamics of Ago-Mediated Silencing Processes

Willkomm, Sarah, Restle, Tobias

Journal:

International Journal of Molecular Sciences

Year:

2015

Language:

english

File:

PDF, 1.92 MB

english, 2015

26

DafA Cycles Between the DnaK Chaperone System and Translational Machinery

Georgeta L. Dumitru, Yvonne Groemping, Dagmar Klostermeier, Tobias Restle, Elke Deuerling, Jochen Reinstein

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 434 KB

english, 2004

27

Oligomeric Nucleic Acids as Antivirals

Mescalchin, Alessandra, Restle, Tobias

Journal:

Year:

2011

Language:

english

File:

PDF, 338 KB

english, 2011

28

Temperature-dependent equilibrium between the open and closed conformation of the p66 subunit of HIV-1 reverse transcriptase revealed by site-directed spin labelling

Oliver Kensch, Tobias Restle, Birgitta M Wöhrl, Roger S Goody, Heinz-Jürgen Steinhoff

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 253 KB

english, 2000

29

Noncovalent Peptide-Mediated Delivery of Chemically Modified Steric Block Oligonucleotides Promotes Splice Correction: Quantitative Analysis of Uptake and Biological Effect

Laufer, Sandra D., Recke, Anna Lena, Veldhoen, Sandra, Trampe, Alexander, Restle, Tobias

Journal:

Oligonucleotides

Year:

2009

Language:

english

File:

PDF, 638 KB

english, 2009

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